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What to consider before taking Zepatier.
You should not use Zepatier if you are allergic to elbasvir or grazoprevir, or if you have:
moderate or severe liver disease.
If you take Zepatier with ribavirin: There may be other reasons you should not take this combination treatment. Tell your doctor about all your medical conditions.
Some medicines can cause unwanted or dangerous effects when used with Zepatier. Your doctor may change your treatment plan if you also use:
St. John’s wort;
HIV or AIDS medication – atazanavir, darunavir, efavirenz, lopinavir, saquinavir, tipranavir; or
seizure medicine – carbamazepine, phenytoin.
Tell your doctor if you have ever had:
liver problems other than hepatitis C;
HIV (human immunodeficiency virus);
a liver transplant, or if you are waiting to have a liver transplant; or
if you use a blood thinner (warfarin, Coumadin, Jantoven) and you have routine “INR” or prothrombin time tests.
It is not known whether Zepatier will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Zepatier is sometimes used in combination with ribavirin. Ribavirin can cause birth defects or death in an unborn baby if the mother or father is using this medicine.
If you are a woman, do not use ribavirin if you are pregnant. You may need to have a negative pregnancy test before taking ribavirin and every month during your treatment.
If you are a man, do not use ribavirin if your sexual partner is pregnant. An unborn baby could be harmed if you have sex with a pregnant woman while you are taking ribavirin.
Both men and women should use at least 2 effective forms of birth control to prevent pregnancy. Keep using 2 forms of birth control for at least 6 months after your last dose of ribavirin.
Tell your doctor right away if a pregnancy occurs while either the mother or the father is using ribavirin.
It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.
Zepatier is not approved for use by anyone younger than 18 years old.